Anti-REG1B Antibody

Cat: 11638-R029

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Anti-REG1B Antibody (Rabbit Monoclonal antibody) General Information

Product name
Anti-REG1B Antibody
Applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human REG1B
Immunogen
Recombinant Human REG1B protein (Catalog#11638-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human REG1B (rh REG1B; Catalog#11638-H08H; NP_006498.1; Met 1-Asn 166).
Source
Monoclonal Rabbit IgG Clone #029
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-REG1B Antibody (Rabbit Monoclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-REG1B Antibody Alternative Names

Anti-PSPS2 Antibody;Anti-REGH Antibody;Anti-REGI-BETA Antibody;Anti-REGL Antibody

REG1B Background Information

Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein which has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas.
Full Name
regenerating islet-derived 1 beta
References
  • Moriizumi S, et al. (1994) Isolation, structural determination and expression of a novel reg gene, human regI beta. Biochim Biophys Acta. 1217(2): 199-202.
  • Sanchez D, et al. (2001) Preferential expression of reg I beta gene in human adult pancreas. Biochem Biophys Res Commun. 284(3): 729-37.
  • Boonyasrisawat W, et al. (2002) Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. Southeast Asian J Trop Med Public Health. 33(2): 365-72.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-REG1B Antibody Rabbit Polyclonal ELISA 90163-RP01
    Anti-REG1B Antibody Rabbit Polyclonal ELISA 90163-T16
    Anti-REG1B Antibody Mouse Monoclonal ELISA 90163-MM05
    Anti-REG1B Antibody Rabbit Polyclonal ELISA,IHC-P 11638-RP02
    Anti-REG1B Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11638-R103
    Anti-REG1B Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 11638-R008
    Anti-REG1B Antibody Rabbit Monoclonal IHC-P 11638-R010
    Anti-REG1B Antibody (HRP) Rabbit Monoclonal ELISA 11638-R103-H
    Anti-REG1B Antibody Rabbit Polyclonal ELISA 11638-RP01
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