Anti-Peroxiredoxin 5 Antibody (Rabbit Polyclonal antibody) General Information
Anti-Peroxiredoxin 5 Antibody
Reacts with: Mouse
Mouse Peroxiredoxin 5
Recombinant Mouse Peroxiredoxin 5 / PRDX5 protein (Catalog#50551-M07E)
Produced in rabbits immunized with purified, recombinant Mouse Peroxiredoxin 5 / PRDX5 (rM Peroxiredoxin 5 / PRDX5; Catalog#50551-M07E; P99029-1; Met 49-Leu 210). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Peroxiredoxin 5 Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Peroxiredoxin 5 Antibody Alternative Names
Anti-AOEB166 Antibody;Anti-AOPP Antibody;Anti-Pmp20 Antibody;Anti-Prdx6 Antibody;Anti-PrxV Antibody
Peroxiredoxin 5 Background Information
Peroxiredoxin-5, also known as Alu corepressor 1, Antioxidant enzyme B166, Liver tissue 2D-page spot 71B, Peroxisomal antioxidant enzyme, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5 and ACR1, is cytoplasm protein which belongs to the?peroxiredoxin 2 family. Peroxiredoxin-5 / PRDX5 reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-5 / PRDX5 is involved in intracellular redox signaling. The Peroxiredoxins / Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.
Seo M.S., et al., 2000, J. Biol. Chem. 275: 20346-54. Declercq J.-P., et al., 2001, J. Mol. Biol. 311:751-9. Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90. Schremmer,B. et al., 2007, Subcell Biochem. 44 :317-44.