Anti-LAMP2 Antibody

Cat: 50791-RP02

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Anti-LAMP2 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-LAMP2 Antibody
Applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse LAMP2
Immunogen
Recombinant Mouse LAMP2 / CD107b protein (Catalog#50791-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse LAMP2 / CD107b (rM LAMP2 / CD107b; Catalog#50791-M08H; P17047-1; Leu 26-Asn 379). LAMP2 / CD107b specific IgG was purified by Mouse LAMP2 / CD107b affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-LAMP2 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-LAMP2 Antibody Alternative Names

Anti-CD107b Antibody;Anti-Lamp-2 Antibody;Anti-Lamp-2a Antibody;Anti-Lamp-2b Antibody;Anti-Lamp-2c Antibody;Anti-LampII Antibody;Anti-LGP-B Antibody;Anti-Mac3 Antibody

LAMP2 Background Information

LAMP2 (Lysosomal-associated membrane protein 2), also known as CD17b (Cluster of Differentiation 17b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
Full Name
lysosomal-associated membrane protein 2
References
  • Maron BJ, et al. (2010) Profound left ventricular remodeling associated with LAMP2 cardiomyopathy. Am J Cardiol. 106(8): 1194-6.
  • Di Blasi C, et al. (2008) Danon disease: a novel LAMP2 mutation affecting the pre-mRNA splicing and causing aberrant transcripts and partial protein expression. Neuromuscul Disord. 18(12): 962-6.
  • Echaniz-Laguna A, et al. (2006) Novel Lamp-2 gene mutation and successful treatment with heart transplantation in a large family with Danon disease. Muscle Nerve. 33(3): 393-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-LAMP2 Antibody Rabbit Polyclonal IHC-P 102348-T08
    Anti-LAMP2 Antibody Rabbit Polyclonal WB,ELISA 50791-T48
    Anti-LAMP2 Antibody Rabbit Monoclonal ELISA 50791-R102
    Anti-LAMP2 Antibody Rabbit Monoclonal FCM 50791-R141
    Anti-LAMP2 Antibody (PE) Rabbit Monoclonal FCM 50791-R141-P
    Anti-LAMP2 Antibody (FITC) Rabbit Monoclonal FCM 50791-R141-F
    Anti-LAMP2 Antibody Rabbit Polyclonal ELISA 50791-RP01
    Anti-LAMP2 Antibody Rabbit Polyclonal WB,IHC-P,ICC/IF,IF,IP 13555-T46
    Anti-LAMP2 Antibody Rabbit Polyclonal ELISA 13555-RP01
    Anti-LAMP2 Antibody Mouse Monoclonal FCM 13555-MM05
    Anti-LAMP2 Antibody Mouse Monoclonal ELISA 13555-MM02
    Anti-LAMP2 Antibody (FITC) Mouse Monoclonal FCM 13555-MM05-F
    Anti-LAMP2 Antibody Mouse Monoclonal IHC-P 13555-MM10
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