NFAT2 / NFATC1 cDNA ORF Clone, Human, N-DDK (Flag®) tag

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NFAT2 / NFATC1 cDNA ORF Clone, Human, N-DDK (Flag®) tag: General Information

Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
2151 bp
Description
Full length Clone DNA of Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 with N terminal Flag tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
Tag Sequence
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

NFAT2 / NFATC1 cDNA ORF Clone, Human, N-DDK (Flag®) tag: Alternative Names

NF-ATC cDNA ORF Clone, Human; NFAT2 cDNA ORF Clone, Human; NFATc cDNA ORF Clone, Human

NFAT2 / NFATC1 Background Information

The nuclear factor of the activated T cell (NFAT) family of transcription factors regulates cytokine gene expression by binding to the promoter/enhancer regions of antigen-responsive genes, usually in cooperation with heterologous DNA-binding partners.The nuclear factor of activated T lymphocytes (NFATC1) signaling has been demonstrated to play important roles in cardiac valve and septal development. Genetic variants in genes involved in NFATC1 signaling may affect their expression and promote the formation of congenital heart disease (CHD). Nuclear factor of activated T cells (NFATC1) was up-regulated in cancers mediating malignant behaviors. The nuclear factor of activated T cell 1 (Nfatc1) locus is a common insertion site for murine tumorigenic retroviruses, suggesting a role of transcription factor NFATc1 in lymphomagenesis.
Full Name
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
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