CD59 qPCR Primer Pairs, Human

Cat: HP104803

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CD59 qPCR Primer Pairs, Human General Information

Target Details

Species:
Human

Product Details

Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.

Application & Quality

Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.

Storage & Shipping

Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages

Unique Primer Design

To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.

Strict Validation Process

Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.

Uniform PCR conditions, Saving time and cost

~100% amplification curve, ensuring the accuracy of the RNA quantitative

CD59 qPCR Primer Pairs, Human Alternative Names

16.3A5 qPCR Primer Pairs, Human;1F5 qPCR Primer Pairs, Human;EJ16 qPCR Primer Pairs, Human;EJ30 qPCR Primer Pairs, Human;EL32 qPCR Primer Pairs, Human;FLJ38134 qPCR Primer Pairs, Human;FLJ92039 qPCR Primer Pairs, Human;G344 qPCR Primer Pairs, Human;HRF-20 qPCR Primer Pairs, Human;HRF20 qPCR Primer Pairs, Human;MAC-IP qPCR Primer Pairs, Human;MACIF qPCR Primer Pairs, Human;MEM43 qPCR Primer Pairs, Human;MGC2354 qPCR Primer Pairs, Human;MIC11 qPCR Primer Pairs, Human;MIN1 qPCR Primer Pairs, Human;MIN2 qPCR Primer Pairs, Human;MIN3 qPCR Primer Pairs, Human;MIRL qPCR Primer Pairs, Human;MSK21 qPCR Primer Pairs, Human;p18-20 qPCR Primer Pairs, Human

CD59 Background Information

CD59 glycoprotein, also known as 20 kDa homologous restriction factor, HRF20, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D).

Full Name
CD59 molecule
References
  • Fletcher CM. et al., 1994, Structure. 2: 185-99.
  • Rudd PM. et al., 1997, J Biol Chem. 272: 7229-44.
  • Kimberley FC. et al., 2007, Mol Immunol. 44 (1-3): 73-81.
  • Gong Y. et al., 2007, Sci China C Life Sci. 50 (6): 773-9.
  • Picariello G. et al., 2008, Proteomics 8: 3833-47.
  • Heibeck TH. et al., 2009, J Proteome Res. 8: 3852-61.
  • CD59 qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    CD59 cDNA ORF Clone in Cloning Vector, Rhesus CG90188-G
    CD59 cDNA ORF Clone, Rhesus, untagged CG90188-UT
    CD59 cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90188-ACG
    CD59 Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90188-ACGLN
    CD59 cDNA ORF Clone, Rhesus, C-OFPSpark® tag CG90188-ACR
    CD59 cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag CG90188-CF
    CD59 cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag CG90188-NF
    CD59 cDNA ORF Clone, Rhesus, C-His tag CG90188-CH
    CD59 cDNA ORF Clone, Rhesus, N-His tag CG90188-NH
    CD59 cDNA ORF Clone, Rhesus, C-HA tag CG90188-CY
    CD59 cDNA ORF Clone, Rhesus, N-HA tag CG90188-NY
    CD59 cDNA ORF Clone, Rhesus, C-Myc tag CG90188-CM
    CD59 cDNA ORF Clone, Rhesus, N-Myc tag CG90188-NM

    CD59 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    CD59 cDNA ORF Clone in Cloning Vector, Rat RG80299-G
    CD59 cDNA ORF Clone, Rat, untagged RG80299-UT
    CD59 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80299-ACGLN
    CD59 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80299-ACG
    CD59 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80299-ACR
    CD59 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80299-CF
    CD59 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80299-NF
    CD59 cDNA ORF Clone, Rat, C-His tag RG80299-CH
    CD59 cDNA ORF Clone, Rat, N-His tag RG80299-NH
    CD59 cDNA ORF Clone, Rat, C-HA tag RG80299-CY
    CD59 cDNA ORF Clone, Rat, N-HA tag RG80299-NY
    CD59 cDNA ORF Clone, Rat, C-Myc tag RG80299-CM
    CD59 cDNA ORF Clone, Rat, N-Myc tag RG80299-NM

    CD59 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CD59 cDNA ORF Clone in Cloning Vector, Human HG16924-U
    CD59 cDNA ORF Clone, Human, untagged HG16924-UT
    CD59 cDNA ORF Clone, Human, untagged HG12474-UT
    CD59 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG16924-ACGLN
    CD59 cDNA ORF Clone, Human, C-GFPSpark® tag HG16924-ACG
    CD59 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG12474-ACGLN
    CD59 cDNA ORF Clone, Human, C-OFPSpark® tag HG16924-ACR
    CD59 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG16924-CF
    CD59 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG16924-NF
    CD59 cDNA ORF Clone, Human, C-His tag HG16924-CH
    CD59 cDNA ORF Clone, Human, N-His tag HG16924-NH
    CD59 cDNA ORF Clone, Human, C-HA tag HG16924-CY
    CD59 cDNA ORF Clone, Human, N-HA tag HG16924-NY
    CD59 cDNA ORF Clone, Human, C-Myc tag HG16924-CM
    CD59 cDNA ORF Clone, Human, N-Myc tag HG16924-NM
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