Schnelle Bestellung

EphB3 / HEK2 Antikörper, Pab von Hasen, Antigen Affinity Purified

  • EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
DatenblattBewertungenÄhnliche ProdukteProtokolle
Mensch EPHB3 Produktinformation zu Antikörpern
Immunogen:Recombinant Human EPHB3 / HEK2 protein (Catalog#13925-H20B1)
Clone ID:
Ig-Typ:Rabbit IgG
Konzentration:
Endotoxin:
Rezeptur:0.2 μm filtered solution in PBS with 5% trehalose
Vorbereitung:Produced in rabbits immunized with purified, recombinant Human EPHB3 / HEK2 (rh EPHB3 / HEK2; Catalog#13925-H20B1; P54753; Gln585-Val998). EPHB3 / HEK2 specific IgG was purified by Human EPHB3 / HEK2 affinity chromatography.
Mensch EPHB3 Antibody IHC Application Image
EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Klicken Sie, um das Bild zu vergrößern]
Caption:
Immunochemical staining of human EPHB3 in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Klicken Sie, um das Bild zu vergrößern]
Caption:
Immunochemical staining of human EPHB3 in human cirrhosis with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Klicken Sie, um das Bild zu vergrößern]
Caption:
Immunochemical staining of human EPHB3 in human colon with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Klicken Sie, um das Bild zu vergrößern]
Caption:
Immunochemical staining of human EPHB3 in human colon carcinoma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
EphB3 / HEK2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Klicken Sie, um das Bild zu vergrößern]
Caption:
Immunochemical staining of human EPHB3 in human gastric cancer with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other EPHB3 Antibody Products
EphB3/HEK2/Eph Receptor B3 Hintergrund

Ephrin type-B receptor 3, also known as EphB3 or HEK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. EphB receptor tyrosine kinases are enriched at synapses, suggesting that these receptors play a role in synapse formation or function. We find that EphrinB binding to EphB induces a direct interaction of EphB with NMDA-type glutamate receptors. This interaction occurs at the cell surface and is mediated by the extracellular regions of the two receptors, but does not require the kinase activity of EphB.

Mensch EphB3/HEK2/Eph Receptor B3 Referenzen
  • Bergemann AD, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4): 471-80.
  • Hock B, et al. (1998) PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. Proc Natl Acad Sci U S A. 95(17): 9779-84.
  • Liu X, et al. (2006) EphB3: an endogenous mediator of adult axonal plasticity and regrowth after CNS injury. J Neurosci. 26(12): 3087-101.
  • Product nameProduct name
    Size / Price
    Katalog: 13925-RP02-50
    Listenpreis: 
    Preis:      (You Save: )

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Bitte beachten: Alle Produkte sind „FÜR FORSCHUNGSZWECKE VORGESEHEN UND DÜRFEN NICHT ZUR DIAGNOSE ODER THERAPIE VERWENDET WERDEN“